Arbaclofen Extended-Release for the Treatment of Spasticity in Multiple Sclerosis: An Open-Label Safety Study (Study OS440-3005)
Background: Despite pharmacologic therapy, people with multiple sclerosis (MS) often experience spasticity, which can worsen with longer...
Arbaclofen Extended-Release for Spasticity in Multiple Sclerosis: Responder Analysis of a Phase 3 Randomized, Placebo-Controlled Clinical Study OS440-3004
Background: Arbaclofen is the active R-enantiomer of racemic baclofen. Arbaclofen extended-release (ER) tablets have demonstrated efficacy...
Characterizing the Relationship between Neurological/Mental Health and Physical Activity Levels in Persons with Multiple Sclerosis
Background: Physical activity is one way that persons with multiple sclerosis (MS) (PwMS) can manage disease symptoms and progression....
Validation and Minimal Detectable Change of the Walking While Talking Test As a Measure of Dual-Task Performance in Ambulatory Individuals with Multiple Sclerosis
Background: Multiple Sclerosis (MS) is a progressive neurodegenerative disease associated with demyelination of the central nervous system...
Attitude and Perception of Multiple Sclerosis Patients Toward Exercise
Background: Contrary to the common belief that physical training for Multiple Sclerosis (MS) patients might exacerbate fatigue and provoke...
A Scoping Review of Task-Oriented Exercise Effects on Motor Function in People with Multiple Sclerosis
Background: Exercise improves cardiorespiratory and musculoskeletal fitness for people with multiple sclerosis (MS). Recent work suggests...
Contradictory Roles of Exercise Participation: A Qualitative Synthesis
Background: Exercise is becoming increasingly medicalized among populations experiencing disability such as those with multiple sclerosis...