Posters

Non-Right-Handedness May be Associated with More Severe Multiple Sclerosis

Background: Because handedness non-right-handedness (NRH) is associated with increased incidence of other auto-immune disorders, Shirani et al. (2019) suggested NRH …

Validating the Clinical Usefulness of the Timed 25-Foot Walk in MS in Routine Clinical Practice

Background: Multiple Sclerosis (MS) is a chronic and degenerative autoimmune disease of the central nervous system which can cause disability …

Cerebrospinal Fluid Protein Is Higher in Males with Multiple Sclerosis: Results from an International Multicenter Cohort

Background: Sex has a differential effect on MS disease severity. Males tend to have a more severe clinical course and …

Predicting Stress Levels and Response to a Self-Management Program Using Participant Demographic, Clinical, and Biomarker Data: A Secondary Analysis

Background: Stress management techniques are actively being pursued for multiple sclerosis (MS); the utility of biomarkers for predicting response to …

Combinatorial Analysis of Plasma and DNA Methylation Biomarkers in African American Patients with Multiple Sclerosis

Background: African American patients are at increased risk of developing severe forms of multiple sclerosis and have been underrepresented in …

Concentration of Evobrutinib, a Brutons Tyrosine Kinase Inhibitor, in Cerebrospinal Fluid during Treatment of Patients with Relapsing Multiple Sclerosis in a Phase 2 Study

Background: Evobrutinib, a highly selective Brutons tyrosine kinase (BTK) inhibitor, demonstrated a low annualized relapse rate (75mg BID, 0.11; 95%CI …

The Effect of Evobrutinib, a Brutons Tyrosine Kinase Inhibitor, on Blood Neurofilament Light Chain Levels in Relapsing Multiple Sclerosis

Background: Evobrutinib is a highly selective Brutons tyrosine kinase inhibitor targeting B cells and myeloid cells. A phase 2 randomized …

2021 CMSC Annual Meeting

nonimaging biomarkers