Poster-Quality of Life and Outcomes
October 25, 2021
Understanding MS Symptoms and Impacts through Semi-Structured Interviews with Clinical Experts and People Living with MS
Background: Multiple sclerosis (MS) is a chronic progressive disease, affecting a broad range of important functions. In order to...
October 25, 2021
Association of Lifestyle Physical Activity with Physical and Cognitive Fatigue in Individuals with Relapsing Remitting Multiple Sclerosis
Background: Fatigue is one of the most common and disabling symptoms of multiple sclerosis (MS). Participation in physical activity is...
October 25, 2021
Combinatorial Analysis of Plasma and DNA Methylation Biomarkers in African American Patients with Multiple Sclerosis
Background: African American patients are at increased risk of developing severe forms of multiple sclerosis and have been underrepresented...
October 25, 2021
Concentration of Evobrutinib, a Brutons Tyrosine Kinase Inhibitor, in Cerebrospinal Fluid during Treatment of Patients with Relapsing Multiple Sclerosis in a Phase 2 Study
Background: Evobrutinib, a highly selective Brutons tyrosine kinase (BTK) inhibitor, demonstrated a low annualized relapse rate (75mg...
October 25, 2021
The Effect of Evobrutinib, a Brutons Tyrosine Kinase Inhibitor, on Blood Neurofilament Light Chain Levels in Relapsing Multiple Sclerosis
Background: Evobrutinib is a highly selective Brutons tyrosine kinase inhibitor targeting B cells and myeloid cells. A phase 2 randomized...
October 25, 2021
National African American Multiple Sclerosis Registry: Advancing Equitable Care and Outcomes for African Americans with Multiple Sclerosis
Background: Historically, multiple sclerosis (MS) has been underdiagnosed among African Americans with MS (AAwMS). Recent evidence suggests...
October 25, 2021
Could Cerebral Autoregulatory Collapse Explain Cognitive Impairment in MS?
Background: Cognitive impairment occurs in almost 70% of multiple sclerosis (MS) patients. The pathophysiology of this impairment is...
October 25, 2021
First Steps Towards Implementation of a Standardized MRI Protocol to Improve Care for People with MS in British Columbia
Background: Magnetic resonance imaging (MRI) is important in the diagnosis and monitoring of people with multiple sclerosis (MS). Using a...
Poster-Disease-modifying Therapy
October 25, 2021
Comparable Ofatumumab Treatment Outcomes in Patients across Racial/Ethnic Groups in the Asclepios I/II and Apolitos Studies
Background: Ofatumumab is a fully human anti-CD20 monoclonal antibody approved by the FDA for treatment of adults with relapsing multiple...
Poster-Disease-modifying Therapy
October 25, 2021
Baseline MRI Predictors of Cognitive Processing Speed in Participants with Secondary Progressive Multiple Sclerosis from the Phase 3 Expand Study
Background: Siponimod showed beneficial effects on magnetic resonance imaging (MRI) lesion activity, total brain and gray matter (GM)...