Tag: PhD

Poster-Neuropathology and Pathogenesis

Altered Expression of the RNA Binding Protein Heterogeneous Nuclear Ribonucleoprotein A1 (A1) Contributes to the Pathogenesis of Neurodegeneration in Multiple Sclerosis

Background: Dysfunctional RNA binding proteins (RBPs) have been shown to contribute to the pathogenesis of neurodegeneration (NDG) in...

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Poster-Neurophysiology; Neuropsychology and Neuropsychiatry

Negative Dual Task Effects Can be Similar in People with Multiple Sclerosis and Controls, but Depend on Processing Time, Not Single Task Performance

Background: Activities of daily living demand simultaneous performance of two or more tasks. Dual task effect (DTE) is the relative change...

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Poster-Neuroimmunology and disease models

RGC-32 Contributes to Reactive Astrocytosis in Experimental Autoimmune Encephalomyelitis By Maintaining a Mature Phenotype

Background: Astrocytes are increasingly recognized as critical contributors to the pathogenesis of multiple sclerosis and experimental...

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Poster-Neurophysiology; Neuropsychology and Neuropsychiatry

FlywheelMS: Stratification of Anxiety and Depression By MS Subtype As Captured in Digitized Health Records

Background: Anxiety and depression are among the most common comorbidities associated with multiple sclerosis (MS). Findings by MS subtype...

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Poster-Non-imaging Biomarkers

Predicting Stress Levels and Response to a Self-Management Program Using Participant Demographic, Clinical, and Biomarker Data: A Secondary Analysis

Background: Stress management techniques are actively being pursued for multiple sclerosis (MS); the utility of biomarkers for predicting...

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Poster-Non-imaging Biomarkers

Concentration of Evobrutinib, a Bruton’s Tyrosine Kinase Inhibitor, in Cerebrospinal Fluid during Treatment of Patients with Relapsing Multiple Sclerosis in a Phase 2 Study

Background: Evobrutinib, a highly selective Bruton’s tyrosine kinase (BTK) inhibitor, demonstrated a low annualized relapse rate (75mg...

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Poster-Neurophysiology; Neuropsychology and Neuropsychiatry

Validation of Paced Auditory Serial Addition Test (PASAT) Regression Normative Data for Performance and Cognitive Fatigability in Multiple Sclerosis

Background: Cognitive fatigability (CF) can be defined as an objective decline in performance that occurs over time during sustained...

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Poster-Methods of Care

Development and Implementation of a Psychoeducational Model for a Pediatric MS Clinic Transition Program

Background: Multiple Sclerosis (MS) is less commonly diagnosed in children than in adults with an estimated prevalence of 5,000 in the US...

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Poster-Methods of Care

Floodlight MS: Using the Jobs-to-be-Done Framework to Identify Unmet Needs in Multiple Sclerosis Care to Support Digital Medical Device Development

Background: Multiple sclerosis (MS) is a chronic disease, and people living with MS (PLwMS) often experience symptoms across numerous...

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