Altered Expression of the RNA Binding Protein Heterogeneous Nuclear Ribonucleoprotein A1 (A1) Contributes to the Pathogenesis of Neurodegeneration in Multiple Sclerosis
Background: Dysfunctional RNA binding proteins (RBPs) have been shown to contribute to the pathogenesis of neurodegeneration (NDG) in...
Negative Dual Task Effects Can be Similar in People with Multiple Sclerosis and Controls, but Depend on Processing Time, Not Single Task Performance
Background: Activities of daily living demand simultaneous performance of two or more tasks. Dual task effect (DTE) is the relative change...
RGC-32 Contributes to Reactive Astrocytosis in Experimental Autoimmune Encephalomyelitis By Maintaining a Mature Phenotype
Background: Astrocytes are increasingly recognized as critical contributors to the pathogenesis of multiple sclerosis and experimental...
FlywheelMS: Stratification of Anxiety and Depression By MS Subtype As Captured in Digitized Health Records
Background: Anxiety and depression are among the most common comorbidities associated with multiple sclerosis (MS). Findings by MS subtype...
Predicting Stress Levels and Response to a Self-Management Program Using Participant Demographic, Clinical, and Biomarker Data: A Secondary Analysis
Background: Stress management techniques are actively being pursued for multiple sclerosis (MS); the utility of biomarkers for predicting...
Clinical and Diagnostic Spectrum of Optic Neuritis: A Single-Center Retrospective Study of Disorders Associated with Multiple Sclerosis, Aquaporin-4 Antibody, and Myelin Oligodendrocyte Glycoprotein Antibody
Background: Optic neuritis (ON) is an immune-mediated optic neuropathy associated with multiple immune-mediated neurological conditions....
Validation of Paced Auditory Serial Addition Test (PASAT) Regression Normative Data for Performance and Cognitive Fatigability in Multiple Sclerosis
Background: Cognitive fatigability (CF) can be defined as an objective decline in performance that occurs over time during sustained...
Development and Implementation of a Psychoeducational Model for a Pediatric MS Clinic Transition Program
Background: Multiple Sclerosis (MS) is less commonly diagnosed in children than in adults with an estimated prevalence of 5,000 in the US...
Floodlight MS: Using the Jobs-to-be-Done Framework to Identify Unmet Needs in Multiple Sclerosis Care to Support Digital Medical Device Development
Background: Multiple sclerosis (MS) is a chronic disease, and people living with MS (PLwMS) often experience symptoms across numerous...