EFFECTIVE ASSESSMENT AND MANAGEMENT STRATEGIES FOR COMPLEX SYMPTOMS OF MS
Multiple sclerosis is a chronic inflammatory and neurodegenerative disease of the CNS that commonly affects young adults. While advances in...
PRESIDENTIAL LECTURE: ESCALATION THERAPY VS. EARLY AGGRESSIVE TREATMENT
As the number of treatments for relapsing forms of multiple sclerosis (MS) increases, advising newly-diagnosed individuals about how to...
Arbaclofen Extended-Release for the Treatment of Spasticity in Multiple Sclerosis: A Randomized, Multi-Center, Placebo-Controlled Clinical Trial (Study OS440-3004)
Background: Arbaclofen, the active R-enantiomer of baclofen, a racemic g-aminobutyric acid-B (GABAB) receptor agonist, has been a mainstay...
Arbaclofen Extended-Release for the Treatment of Spasticity in Multiple Sclerosis: An Open-Label Safety Study (Study OS440-3005)
Background: Despite pharmacologic therapy, people with multiple sclerosis (MS) often experience spasticity, which can worsen with longer...
Arbaclofen Extended-Release for Spasticity in Multiple Sclerosis: Responder Analysis of a Phase 3 Randomized, Placebo-Controlled Clinical Study OS440-3004
Background: Arbaclofen is the active R-enantiomer of racemic baclofen. Arbaclofen extended-release (ER) tablets have demonstrated efficacy...