Tag: Basel

Poster-Quality of Life and Outcomes

Patient-Reported Outcome Measures in Multiple Sclerosis Clinical Trials: Critical Assessment and Insights from People Living with Multiple Sclerosis

Background: Multiple sclerosis (MS) clinical trials often include patient-reported outcomes (PROs) to quantify treatment effects not...

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Poster-Relapse Therapy

Long-Term Safety of Satralizumab in Neuromyelitis Optica Spectrum Disorder: Results from the Open-Label Extension Periods of Sakurasky and Sakurastar

Background: Satralizumab reduced relapse risk vs placebo in neuromyelitis optica spectrum disorder (NMOSD) patients and had a favourable...

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Poster-Quality of Life and Outcomes

Understanding MS Symptoms and Impacts through Semi-Structured Interviews with Clinical Experts and People Living with MS

Background: Multiple sclerosis (MS) is a chronic progressive disease, affecting a broad range of important functions. In order to...

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Poster-Neurophysiology; Neuropsychology and Neuropsychiatry

FlywheelMS: Stratification of Anxiety and Depression By MS Subtype As Captured in Digitized Health Records

Background: Anxiety and depression are among the most common comorbidities associated with multiple sclerosis (MS). Findings by MS subtype...

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Poster-Non-imaging Biomarkers

The Effect of Evobrutinib, a Bruton’s Tyrosine Kinase Inhibitor, on Blood Neurofilament Light Chain Levels in Relapsing Multiple Sclerosis

Background: Evobrutinib is a highly selective Bruton’s tyrosine kinase inhibitor targeting B cells and myeloid cells. A phase 2 randomized...

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Poster-Methods of Care

Floodlight MS: Utilizing Rapid Prototyping and Human Factors Studies to Develop a Digital Medical Device for Patient-Centric MS Care

Background: In multiple sclerosis (MS), subtle disease progression starts early despite initial presentation. Early neurologic damage can...

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Poster-Methods of Care

Floodlight MS: Using the Jobs-to-be-Done Framework to Identify Unmet Needs in Multiple Sclerosis Care to Support Digital Medical Device Development

Background: Multiple sclerosis (MS) is a chronic disease, and people living with MS (PLwMS) often experience symptoms across numerous...

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Poster-Disease-modifying Therapy

Efficacy of Ofatumumab on Microglial Activity in Patients with Relapsing Forms of Multiple Sclerosis: Interim Analysis

INTRODUCTION Ofatumumab, a fully-human anti-CD20 monoclonal antibody, is indicated for the treatment of relapsing forms of multiple...

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Poster-Imaging

Neural Correlates of Hand Motor Function Revealed By Structural MR Imaging: A Smartphone-Based Remote Assessment Study in People with MS

Background: Regional gray matter pathology is associated with hand motor impairment in people with multiple sclerosis (PwMS). Objectives:...

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Poster-Disease-modifying Therapy

Comparable Ofatumumab Treatment Outcomes in Patients across Racial/Ethnic Groups in the Asclepios I/II and Apolitos Studies

Background: Ofatumumab is a fully human anti-CD20 monoclonal antibody approved by the FDA for treatment of adults with relapsing multiple...

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