RGC-32 Contributes to Reactive Astrocytosis in Experimental Autoimmune Encephalomyelitis By Maintaining a Mature Phenotype
Background: Astrocytes are increasingly recognized as critical contributors to the pathogenesis of multiple sclerosis and experimental...
Effect of Ocrelizumab on Antibody Responses to EBV
Background: The association between multiple sclerosis (MS) and Epstein-Barr virus (EBV) is well known. Previously, it’s been shown...
Comparing Infection-Related Outcomes By Sex in Patients with Multiple Sclerosis and Matched Controls Using Administrative Claims Data
Background: Few population-level sex-based risk estimates of specific infections exist for US patients with multiple sclerosis (MS)....
Clinical and Diagnostic Spectrum of Optic Neuritis: A Single-Center Retrospective Study of Disorders Associated with Multiple Sclerosis, Aquaporin-4 Antibody, and Myelin Oligodendrocyte Glycoprotein Antibody
Background: Optic neuritis (ON) is an immune-mediated optic neuropathy associated with multiple immune-mediated neurological conditions....
Mucosal Associated Invariant T (MAIT) Cells Show Defective Activation in People with Multiple Sclerosis
Background: mucosal associated invariant T (MAIT) cells are innate-like T cells expressing an invariant TCR ? chain with a limited number...
Enhanced IL2 Induced Activation of STAT5 in Effector CD4 and CD8 T Cell Populations from Treatment Naïve Relapsing Multiple Sclerosis
Background: Polymorphisms within the IL2RA gene (CD25) is a risk factor for multiple sclerosis (MS), raising the possibility that IL2...