Continued Expansion of a Multiple Sclerosis Pharmacy Program
Background: Kaiser Permanente Washington (KPWA) launched a Multiple Sclerosis (MS) Pharmacy Program in June 2014 to support patients on...
Altered Expression of the RNA Binding Protein Heterogeneous Nuclear Ribonucleoprotein A1 (A1) Contributes to the Pathogenesis of Neurodegeneration in Multiple Sclerosis
Background: Dysfunctional RNA binding proteins (RBPs) have been shown to contribute to the pathogenesis of neurodegeneration (NDG) in...
Evaluation of Apathy in Multiple Sclerosis
Background: Features of apathy include lack of initiation, lack of interest, reduced spontaneity, indifference, and reduced self-awareness....
Validating the Clinical Usefulness of the Timed 25-Foot Walk in MS in Routine Clinical Practice
Background: Multiple Sclerosis (MS) is a chronic and degenerative autoimmune disease of the central nervous system which can cause...
Development and Implementation of a Psychoeducational Model for a Pediatric MS Clinic Transition Program
Background: Multiple Sclerosis (MS) is less commonly diagnosed in children than in adults with an estimated prevalence of 5,000 in the US...
RGC-32 Contributes to Reactive Astrocytosis in Experimental Autoimmune Encephalomyelitis By Maintaining a Mature Phenotype
Background: Astrocytes are increasingly recognized as critical contributors to the pathogenesis of multiple sclerosis and experimental...
Mucosal Associated Invariant T (MAIT) Cells Show Defective Activation in People with Multiple Sclerosis
Background: mucosal associated invariant T (MAIT) cells are innate-like T cells expressing an invariant TCR ? chain with a limited number...
Enhanced IL2 Induced Activation of STAT5 in Effector CD4 and CD8 T Cell Populations from Treatment Naïve Relapsing Multiple Sclerosis
Background: Polymorphisms within the IL2RA gene (CD25) is a risk factor for multiple sclerosis (MS), raising the possibility that IL2...
Identifying Prospective Memory Deficits in MS with a Single Task from the Memory for Intentions Test: An IRT and ROC Analysis
Background: While many persons with multiple sclerosis (PwMS) have prospective memory (PM) issues, which can have an impact on everyday...