This symposium will explore the mechanisms by which the immune system participates in the pathogenesis of MS, highlighting potential targets for therapeutic intervention. In the different talks, we will focus on the immune cells that induce the damage to the CNS, specifically on T cells and macrophages. We will investigate the factors that lead to the development of autoreactive T cells, including the gut microbiota, different metabolic factors as well as the local milieu in the CNS. We will then describe the cytokines produced by T cells of MS patients and how they may contribute to the disease development.
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